So is there any foreseeable way of solving it without disabling Defender?

I suppose I can try and rebuild it.. though I don't know why it would have failed the first time :/ Let me know what version you need and I'll see if I can upload it here.

yeah ok.
I actually got this issue from a prospect, I will check with him and get back to you.

Is this still an issue? I'm assigning this back, as I would imagine that whoever actually got the bug would be able to send the proper diagnostic information to Microsoft.

If thye are a Microsoft enterprise customer, they might get more information via https://www.microsoft.com/en-us/security/portal/submission/submit.aspx. As it stands, I can submit the file independently, but only hope to wait and see that they actually look at it.

FWIW:

https://www.microsoft.com/en-us/security/portal/submission/SubmissionHistory.aspx?SubmissionId=0b8be99e-257b-4fee-8214-85a588c5ec0c

I'm closing this as 'Cannot Reproduce'. For some reason I can't assign the bug back to you, but included is a link showing that MS itself doesn't detect a virus/malware etc.

I tried both a locally built version of the file, and one I downloaded directly from PyPi